HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-Hydroxybenzo(b)thiophene-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | N-(3-Cyano-1-benzothiophen-2-yl)acetamide | HCID 21286564 | — |
| Product | 2-Hydroxybenzo(b)thiophene-3-carboxamide | HCID 14257934 | — |
Reaction Steps
A mixture of 2-acetamido-3-cyanobenzo(b)thiophene (2.2 g, 0.01 m), ethanol (25 ml), water (15 ml) and concentrated hydrochloric acid (25 ml) is heated under reflux for 12 hours. The reaction mixture is diluted with water, aged and filtered to yield 2-hydroxybenzo(b)thiophene-3-carboxamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04782080 |
| Source dataset | uspto-grants-1988_11 |
| ORD ID | ord-dc6bc83cd6e0450db766e10d8abd759a |
| Source note | uspto-grants-1988_11 |