Hydrochloric Acid → HCID 54478558, compound

Participants

Reaction Steps

An ethyl ether solution of 13.8 g (0.05 moles) of 2,3-dihydro-2,3,5-trimethyl-6-(2-methyl-2-bromo-1-oxoethyl)-4H-pyran-4-one was dripped to ethylmagnesium bromide prepared from 1.5 g of magnesium and 6.6 g of ethyl bromide in 200 ml of ethyl ether. After the ether solution was agitated at room temperature for 1 hour, 1.2 g (0.05 moles) of magnesium were added and the mixture was agitated for 3 more hours. The reaction mixture was poured into 100 ml of dilute hydrochloric acid to concentrate the ether layer, thereby providing 7.9 g of 2,3-dihydro-2,3,5-trimethyl-6-(1-methyl-1-butenyl)-4H-pyran-4-one. The yield was 79%.

Provenance & Evidence