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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2231607Generated: October 25, 2026

5-Chloro-2-methyl-4-isothiazolin-3-one → 4,5-Dichloro-2-methyl-4-isothiazolin-3-one

https://huagongshe.com/reaction/2231607

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Chloro-2-methyl-4-isothiazolin-3-oneHCID 33344—
Reactant2-n-Octyl-4-isothiazolin-3-oneHCID 33528—
ReactantMethylisothiazolinoneHCID 39800—
ReactantKathonHCID 41679—
Reactant1H-1lambda~4~,2-Thiazol-1-oneHCID 15739356—
Product4,5-Dichloro-2-methyl-4-isothiazolin-3-oneHCID 147017—

Reaction Steps

A number of isothiazolone compounds useful as component (B) in the present invention are available commercially from, for example, the Rohm & Haas Company, Philadelphia, Pa. under various trade names. For example, 2-n-octyl-3-isothiazolone is available under the general trade name Skane M-8. The corresponding 4,5-dichloro-n-octyl-derivative is available under the trade designation Kathon 287. The product 5-chloro-2-methyl-3-isothiazolone is available under the general trade designation Kathon 886. Also available commercially from Rohm & Haas is a mixture of 5-chloro-2-methyl-3-isothiazolone and 2-methyl-3-isothiazolone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04783221
Source datasetuspto-grants-1988_11
ORD IDord-34126d6ec02b4ffcb97addc0ae4e5e45
Source noteuspto-grants-1988_11