反应详情

Methylsulphonyl isocyanate (3.15 g) was added dropwise to a solution of 2-anilino-4,6-dimethylpyrimidine (3.98 g) in toluene (40 ml). The mixture was then stirred for 2 hours at room temperature. The solid was separated and dried in vacuo, to give 1-(4,6-dimethylpyrimidine-2-yl)-3-methylsulphonyl-1-phenylurea, m.p. 186°-192°. (Compound 5).

1. customThe solid was separated
2. customdried in vacuo