HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 13686259, compound → N-[1(S)-ethoxycarbonyl-2-(4-nitrophenyl)ethyl]-(S)-alanine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 13686259 | HCID 13686259 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | N-[1(S)-ethoxycarbonyl-2-(4-nitrophenyl)ethyl]-(S)-alanine | HCID 13686261 | — |
Reaction Steps
Add cold trifluoroacetic acid (600 ml) (ice bath) to N-[1(S)-ethoxycarbonyl-2-(4-nitrophenyl)ethyl](S)-alanine, t-butyl ester (25.5 g) and stir the resulting mixture at room temperature under a nitrogen atmosphere for 4 hours. Concentrate the solution in vacuo to give a viscous oil. Triturate the viscous oil with hexane (3 l) and then ether to yield N-[1(S)-ethoxycarbonyl-2-(4-nitrophenyl)ethyl]-(S)-alanine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04783444 |
| Source dataset | uspto-grants-1988_11 |
| ORD ID | ord-6b03ef57c40b4a40bc911a34a1fa1cef |
| Source note | uspto-grants-1988_11 |