HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Ether → 2-Amino-5-iodo-3-methylbenzoic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | Iodine chloride | HCID 24640 | — |
| Reactant | 2-Amino-3-methylbenzoic acid | HCID 78101 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 2-Amino-5-iodo-3-methylbenzoic Acid | HCID 11231233 | — |
Reaction Steps
Iodine monochloride (28.9 g) was added over 0.5 hours to a stirred solution of 2-amino-3-methylbenzoic acid (24.5 g) (Aldrich Chemical Co. Ltd.) in acetic acid (250 cm3). After 24 hours ether (250 cm3) was added and the mixture was filtered. The solid material was dried in vacuo to afford the title compound, m.p. 214° (38.6 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04783467 |
| Source dataset | uspto-grants-1988_11 |
| ORD ID | ord-9df925309c8c4af18d61b70f66256832 |
| Source note | uspto-grants-1988_11 |