Glycine ethyl ester → HCID 178472683, compound

HRID 2231668Notes

Reaction equation

HRID 2231668 reaction equation
[NH2:1][CH2:2][C:3]([O:5][CH2:6][CH3:7])=[O:4].[NH2:8][C:9]1[C:16]([CH3:17])=[CH:15][C:14]([C:18]2[CH:19]=[CH:20][C:21]([OH:24])=[N:22][CH:23]=2)=[CH:13][C:10]=1[CH:11]=O.[H][H]>[Pd]>[NH2:8][C:9]1[C:16]([CH3:17])=[CH:15][C:14]([C:18]2[CH:19]=[CH:20][C:21]([OH:24])=[N:22][CH:23]=2)=[CH:13][C:10]=1[CH2:11][NH:1][CH2:2][C:3]([O:5][CH2:6][CH3:7])=[O:4]

Participants

5

Reactant 3

HCID 12176Glycine ethyl esterHCID 178418361HCID 178418361, compoundHCID 178422731HCID 178422731, compound

Product 1

HCID 178472683HCID 178472683, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

The title compound was prepared similarly to Preparation 25 using ethyl glycinate and 2-amino-5-(2-hydroxypyrid-5-yl)-3-methylbenzaldehyde followed by hydrogen over Pd/C: ##STR58##

Sources & evidence

ORD record
ord-98c7efdc641c4aa4b60f791749678034
Source dataset
uspto-grants-1988_11
Patent number
US04783467

Reaction notes

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