HuagongsheHuagongshe Chemistry Print Report · For research reference only
Indole → 7-Ethyl-1,1a,2,3,8,8b-hexahydrocyclopropa[a]-carbazole-8b-acetic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Indole | HCID 798 | — |
| Reactant | (2-Ethylphenyl)hydrazine | HCID 2733210 | — |
| Reactant | 2-Oxobicyclo[4.1.0]heptane-1-acetic Acid Ethyl Ester | HCID 14770207 | — |
| Product | 7-Ethyl-1,1a,2,3,8,8b-hexahydrocyclopropa[a]-carbazole-8b-acetic Acid | HCID 14302244 | — |
Reaction Steps
The title compound was prepared from 2-oxobicyclo[4.1.0]heptane-1-acetic acid ethyl ester by a Fisher indole reaction with 2-ethylphenylhydrazine followed by ester hydrolysis as described in Example 1, Step 6, m.p. 154°-156° C. (foams).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04783479 |
| Source dataset | uspto-grants-1988_11 |
| ORD ID | ord-f46c9e10c14d43f1ae07df682059d662 |
| Source note | uspto-grants-1988_11 |