Hydrochloric Acid → HCID 14274479, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 5.0 g (7 mmol) of diphenylbis(3,5-di-tert-butyl-4-trimethylsilyloxyphenyl)silane in 30 ml of tetrahydrofuran at 0° C. is added dropwise a solution of 4.3 g (14 mmol) of tetrabutylammonium fluoride trihydrate in 35 ml of tetrahydrofuran. The reaction mixture is stirred for 5 minutes at 0° C. and to it is added dropwise a solution of 2.2 g (62 mmol) of concentrated hydrochloric acid in 10 ml of tetrahydrofuran. The solvent is removed in vacuo and to the residue is added 250 ml of diethylether. The solution is extracted (3×100 ml) with water. The organic phase is dried over anhydrous sodium sulfate and the solvent is removed in vacuo to give 4.0 grams of a white solid. The crude product is recrystallized from heptane to give 3.0 g (75%) of product as white crystals; mp. 193°-194.5° C.

Provenance & Evidence