Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → (+/-)-7-methoxy-6-[2-hydroxy-3-(4-phenyl-1-piperazinyl)propoxy]-2H-1-benzopyran-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 1-Phenylpiperazine | HCID 7096 | — |
| 반응물 | 7-methoxy-6-(oxiranylmethoxy)-2H-1-benzopyran-2-one | HCID 19927672 | — |
| 용매 | Ethanol | HCID 702 | — |
| 용매 | Methanol | HCID 887 | — |
| 용매 | Isopropanol | HCID 3776 | — |
| 생성물 | (+/-)-7-methoxy-6-[2-hydroxy-3-(4-phenyl-1-piperazinyl)propoxy]-2H-1-benzopyran-2-one | HCID 19927697 | 99% |
반응 단계
Method C (5 d at 40° C.); starting materials: 7-methoxy-6-(oxiranylmethoxy)-2H-1-benzopyran-2-one and 1-phenylpiperazine; yield 99%; fusion point 160°-162° C. (from isopropanol and ethanol). Hydrochloride: method F; yield 78%; fusion point 222°-225° C. (from isopropanol, ethanol and methanol).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05428038 |
| 출처 데이터셋 | uspto-grants-1995_06 |
| ORD ID | ord-276aa49dfb0348d181a099581cff2403 |
| 출처 메모 | uspto-grants-1995_06 |