HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 1,2,3,4-tetrahydro-3-isoquinolinecarboxylate → N-(N'-acetylsarcosyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 1,2,3,4-tetrahydro-3-isoquinolinecarboxylate | HCID 652898 | — |
| Reactant | N-Acetyl-N-methylglycine | HCID 10975514 | — |
| Catalyst | Lindlars catalyst | HCID 131709914 | — |
| Product | N-(N'-acetylsarcosyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic ethyl ester | HCID 21284821 | — |
Reaction Steps
This compound can be prepared by condensing 1,2,3,4-tetrahydroisoquinoline-3-carboxylic ethyl ester with N-acetylsarcosine according to the above-described methods; the corresponding acid can be prepared via catalytic hydrogenation of the product ester using Lindlar's catalyst or via base hydrolysis.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04785003 |
| Source dataset | uspto-grants-1988_11 |
| ORD ID | ord-c0644c28721d421f812e0e1e7a458b3e |
| Source note | uspto-grants-1988_11 |