HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylacetic Acid → Phenylacetyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylacetic Acid | HCID 999 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Phenylacetyl chloride | HCID 7679 | 99.6% |
Reaction Steps
A mixture of 27.2 g (0.2 moles) phenylacetic acid and 28 g (0.22 moles) oxalyl chloride in 150 ml methylene chloride were stirred for 24 hours. Excess reagent and solvent were removed by stripping to give 30.8 g of phenylacetyl chloride, which was used in step (b) without further isolation.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04785019 |
| Source dataset | uspto-grants-1988_11 |
| ORD ID | ord-1f6b6937e5114db3a8bfcd3cc99d90c2 |
| Source note | uspto-grants-1988_11 |