HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glycine methyl ester hydrochloride → HCID 13364783, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glycine methyl ester hydrochloride | HCID 122755 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | 2-(2,5-Dioxohexyl)-1H-isoindole-1,3(2H)-dione | HCID 12348451 | — |
| Solvent | Acetic acid 10-acetoxymethyl-anthracen-9-ylmethyl ester | HCID 613145 | — |
| Product | HCID 13364783 | HCID 13364783 | — |
Reaction Steps
18.1 g (0.07 mol) of 6-phthalimido-2,5-hexanedione, 10.0 g (0.08 mol) of glycine methyl ester hydrochloride and 6.6 g (0.08 mol) of sodium acetate are stirred in 300 ml of acetic at 80° C. for 3 hours. After the mixture has been concentrated, the residue is taken up in aqueous sodium bicarbonate solution, the mixture is extracted with methylene chloride, the extract is dried and concentrated and the residue is recrystallised from methanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04785010 |
| Source dataset | uspto-grants-1988_11 |
| ORD ID | ord-5c8770f5dc90416d84e3256928d6ac13 |
| Source note | uspto-grants-1988_11 |