N-(2-aminoethyl)acetamide → HCID 13364785, compound

HRID 2231868Notes

Reaction equation

HRID 2231868 reaction equation
[C:1]1(=[O:19])[N:5]([CH2:6][C:7](=O)[CH2:8][CH2:9][C:10](=O)[CH3:11])[C:4](=[O:14])[C:3]2=[CH:15][CH:16]=[CH:17][CH:18]=[C:2]12.[C:20]([NH:23][CH2:24][CH2:25][NH2:26])(=[O:22])[CH3:21]>C(O)(=O)C>[C:20]([NH:23][CH2:24][CH2:25][N:26]1[C:10]([CH3:11])=[CH:9][CH:8]=[C:7]1[CH2:6][N:5]1[C:4](=[O:14])[C:3]2=[CH:15][CH:16]=[CH:17][CH:18]=[C:2]2[C:1]1=[O:19])(=[O:22])[CH3:21]

Participants

4

Reactant 2

HCID 66082N-(2-aminoethyl)acetamideHCID 123484512-(2,5-Dioxohexyl)-1H-isoindole-1,3(2H)-dione

Product 1

HCID 13364785HCID 13364785, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

4.6 g (0.018 mol) of 6-phthalimido-2,5-hexanedione and 1.8 g (0.018 mol) of 2-(acetylamino)-ethylamine are stirred in 120 ml of acetic acid at 80° C. for 4 hours. Working up is carried out as described in Example 1:

Sources & evidence

ORD record
ord-8d6e1aa8a225439ea146b8ecced69761
Source dataset
uspto-grants-1988_11
Patent number
US04785010

Reaction notes

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