Sodium Acetate → HCID 13364790, compound

HRID 2231873Notes

Reaction equation

HRID 2231873 reaction equation
[C:1]1(=[O:19])[N:5]([CH2:6][C:7](=O)[CH2:8][CH2:9][C:10](=O)[CH3:11])[C:4](=[O:14])[C:3]2=[CH:15][CH:16]=[CH:17][CH:18]=[C:2]12.Cl.[NH2:21][CH2:22][C:23]([NH2:25])=[O:24].C([O-])(=O)C.[Na+]>C(O)(=O)C>[NH2:25][C:23]([CH2:22][N:21]1[C:10]([CH3:11])=[CH:9][CH:8]=[C:7]1[CH2:6][N:5]1[C:4](=[O:14])[C:3]2=[CH:15][CH:16]=[CH:17][CH:18]=[C:2]2[C:1]1=[O:19])=[O:24]

Participants

5

Reactant 3

HCID 517045Sodium AcetateHCID 2723639Glycinamide hydrochlorideHCID 123484512-(2,5-Dioxohexyl)-1H-isoindole-1,3(2H)-dione

Product 1

HCID 13364790HCID 13364790, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

5.2 g (0.02 mol) of 6-phthalimido-2,5-hexanedione, 2,3 g (0.02 mol) of glycine amide hydrochloride and 1.7 g (0.02 mol) sodium acetate are stirred in 70 ml of acetic acid at 80° C. for 3 hours and the mixture is worked up as in Example 1.

Sources & evidence

ORD record
ord-42ed630b073843079263d215c06d43c1
Source dataset
uspto-grants-1988_11
Patent number
US04785010

Reaction notes

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