Aminoacetonitrile sulfate (1:1) → HCID 13534392, compound

HRID 2231881Notes

Reaction equation

HRID 2231881 reaction equation
[C:1]1(=[O:19])[N:5]([CH2:6][C:7](=O)[CH2:8][CH2:9][C:10](=O)[CH3:11])[C:4](=[O:14])[C:3]2=[CH:15][CH:16]=[CH:17][CH:18]=[C:2]12.S(O)(O)(=O)=O.[NH2:25][CH2:26][C:27]#[N:28].C([O-])(=O)C.[Na+]>COCCOC>[C:26]([CH2:27][N:28]1[C:10]([CH3:11])=[CH:9][CH:8]=[C:7]1[CH2:6][N:5]1[C:4](=[O:14])[C:3]2=[CH:15][CH:16]=[CH:17][CH:18]=[C:2]2[C:1]1=[O:19])#[N:25]

Participants

5

Reactant 3

HCID 196971Aminoacetonitrile sulfate (1:1)HCID 517045Sodium AcetateHCID 123484512-(2,5-Dioxohexyl)-1H-isoindole-1,3(2H)-dione

Product 1

HCID 13534392HCID 13534392, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

10.4 g (0.04 mol) of 6-phthalimido-2,5-hexanedione, 6.2 g (0.04 mol) of aminoacetonitrile sulphate and 6.8 g (0.08 mol) of sodium acetate are stirred in 200 ml of ethylene glycol dimethyl ether at 80° C. for 16 hours and the mixture is worked up as in Example 27.

Sources & evidence

ORD record
ord-e01492bea8bc42d88315c1f2651b5e44
Source dataset
uspto-grants-1988_11
Patent number
US04785010

Reaction notes

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