Ammonia → HCID 21285253, compound

HRID 2231956Notes

Reaction equation

HRID 2231956 reaction equation
[C:1]([C:3]1[C:4]([N:6]([CH3:12])[C:7](=[O:11])[C:8]=1OC)=[O:5])#[N:2].[NH3:13]>>[NH2:13][C:8]1[C:7](=[O:11])[N:6]([CH3:12])[C:4](=[O:5])[C:3]=1[C:1]#[N:2]

Participants

3

Reactant 2

HCID 222AmmoniaHCID 21285245HCID 21285245, compound

Product 1

HCID 21285253HCID 21285253, compoundYield 83%

Procedure

120 parts of 2-cyano-3-methoxy-N-methylmaleimide are dissolved in 600 parts of methylglycol and 13.5 parts of ammonia are then passed into the ice-cooled solution. Stirring is then continued for 3 hours at room temperature, and the resulting precipitate is filtered off under suction, washed with methanol and then with water, and dried to give 90 parts (83% of theory) of 3-amino-2-cyano-N-methylmaleimide.

Workup

  1. temperaturecooled solution
  2. filtrationthe resulting precipitate is filtered off under suction
  3. washwashed with methanol
  4. dry with materialwith water, and dried

Sources & evidence

ORD record
ord-d9517e8d35684c089bddcb54c754d6f6
Source dataset
uspto-grants-1988_11
Patent number
US04785116

Reaction notes

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