反应详情

8.2 g of 5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid are heated to 300°. After completion of the carbon dioxide evolution, the residue is left to cool and the material is recrystallized from chloroform/hexane. After drying, there is obtained 4,5-dihydro-5-methyl-6H-imidazo[1,5-a][1,4]benzodiazepin-6-one of melting point 212°-213°.

1. temperatureto cool
2. customthe material is recrystallized from chloroform/hexane
3. customAfter drying