HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Isoquinolin-4-yl)but-3-yn-1-ol → (E)-4-(4-isoquinolinyl)-3-buten-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Isoquinolin-4-yl)but-3-yn-1-ol | HCID 10631793 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | (E)-4-(4-isoquinolinyl)-3-buten-1-ol | HCID 14750832 | 96.1% |
Reaction Steps
A solution of 3.4 g of 4-(4-isoquinolinyl)-3-butyn-1-ol in 35 mL of ethanol was hydrogenated over 0.35 g of 10% Pd/C at room temperature and atmospheric pressure for 5 hours. The catalyst was removed by filtration and the filtrate was evaporated to yield 3.3 g of (E)-4-(4-isoquinolinyl)-3-buten-1-ol as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04786646 |
| Source dataset | uspto-grants-1988_11 |
| ORD ID | ord-4f64644b62bc4df39db6ba6ac21a6959 |
| Source note | uspto-grants-1988_11 |