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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2232211Generated: November 2, 2026

Thymidine → 1-(2-Deoxy-5-O-(triphenylmethyl)pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione

https://huagongshe.com/reaction/2232211

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThymidineHCID 5789—
ReactantTrityl chlorideHCID 6456—
SolventPyridineHCID 1049—
Product1-(2-Deoxy-5-O-(triphenylmethyl)pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dioneHCID 514178—

Reaction Steps

This compound was prepared from thymidine and triphenylmethyl chloride in dry pyridine by the procedure of Horwitz and Urbanski.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04788181
Source datasetuspto-grants-1988_11
ORD IDord-e0445b60f88040ca807c3df4922c7ec5
Source noteuspto-grants-1988_11