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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2232218Generated: October 31, 2026

4-[3-(amino)propoxy]-N,N-dimethyl-2-thiophenemethanamine → 1-Amino-2-[3-(5-dimethylaminomethyl-3-thienyloxy)propylamino]cyclobutene-3,4-dione

https://huagongshe.com/reaction/2232218

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[3-(amino)propoxy]-N,N-dimethyl-2-thiophenemethanamineHCID 12926524—
Reactant3-Amino-4-methoxycyclobut-3-ene-1,2-dioneHCID 13452205—
Product1-Amino-2-[3-(5-dimethylaminomethyl-3-thienyloxy)propylamino]cyclobutene-3,4-dioneHCID 21283044—

Reaction Steps

An equimolar mixture of 4-[3-(amino)propoxy]-N,N-dimethyl-2-thiophenemethanamine [prepared according to the procedure described in published European patent application No. 27,744] and 1-amino-2-methoxycyclobutene-3,4-dione is reacted according to the general procedure of Example 19 to yield the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04788184
Source datasetuspto-grants-1988_11
ORD IDord-ed12671345bc47b9b77b41b1d69b68e0
Source noteuspto-grants-1988_11