反应详情

6-Chloro-3-(4-methoxyphenyl)-1,2,4-triazolo[3,4-a]phthalazine (0.5 mole) and fused anhydrous sodium acetate in acetic acid are heated to the reflux temperature for about 1 hour. The solvent is evaporated under reduced pressure, the residue is then taken up with water, collected by filtration, and crystallized from ethanol/chloroform. The product of the title is thus obtained in a 85% yield. M.p. 307°-309° C.

1. temperatureare heated to the reflux temperature for about 1 hour
2. customThe solvent is evaporated under reduced pressure
3. filtrationcollected by filtration
4. customcrystallized from ethanol/chloroform
5. customThe product of the title is thus obtained in a 85% yield