HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-N,N-dimethyl-1-propanamine → N-[4-[3-(Dimethylamino)propoxy]phenyl]-4-(3-pyridinyl)-2-pyrimidinamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-N,N-dimethyl-1-propanamine | HCID 66960 | — |
| Reactant | 4-[[4-(3-Pyridinyl)-2-pyrimidinyl]amino]phenol | HCID 14347190 | — |
| Product | N-[4-[3-(Dimethylamino)propoxy]phenyl]-4-(3-pyridinyl)-2-pyrimidinamine | HCID 14347180 | — |
Reaction Steps
A 5.46 g portion of 4-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenol was reacted with 3-dimethylaminopropyl chloride by the procedure of Example 255, giving 2.9 g of the desired product, mp 85°-87° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04788195 |
| Source dataset | uspto-grants-1988_11 |
| ORD ID | ord-a9935b5fb00e4d85aaad6776b15ed0be |
| Source note | uspto-grants-1988_11 |