HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-(2-Thienyl)thiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2-Bromo-1,1-dimethoxyethane | HCID 81672 | — |
| Reactant | 2-Thiophenecarbothioamide | HCID 737237 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-(2-Thienyl)thiazole | HCID 547510 | 168.3% |
Reaction Steps
In a manner similar to Step B of Example 1, the reaction of 13.3 grams (0.027 mole) of (thien-2-yl)thiocarboxamide with 16.0 grams (0.0945 mole) of bromoacetaldehyde dimethyl acetal and 2 ml of concentrated hydrochloric acid in 250 ml of ethanol yielded 7.6 grams of 2-(thien-2-yl)thiazole as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04788207 |
| Source dataset | uspto-grants-1988_11 |
| ORD ID | ord-25610fb6de494cc089d6090a70ee6cbd |
| Source note | uspto-grants-1988_11 |