Methanesulfonyl chloride → HCID 21283550, compound

HRID 2232399Notes

Reaction equation

HRID 2232399 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH2:13][CH2:12][N:11]([C:14]3[N:15]([CH3:20])[C:16]([CH3:19])=[CH:17][N:18]=3)[CH2:10][CH2:9]2)=[CH:4][CH:3]=1.[CH3:21][S:22](Cl)(=[O:24])=[O:23]>>[CH3:20][N:15]1[C:16]([CH3:19])=[CH:17][N:18]=[C:14]1[N:11]1[CH2:10][CH2:9][N:8]([C:5]2[CH:4]=[CH:3][C:2]([NH:1][S:22]([CH3:21])(=[O:24])=[O:23])=[CH:7][CH:6]=2)[CH2:13][CH2:12]1

Participants

3

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 21283521HCID 21283521, compound

Product 1

HCID 21283550HCID 21283550, compound

Procedure

Treatment of 1-(4-aminophenyl)-4-(1,5-dimethylimidazol-2-yl)piperazine with methanesulphonylchloride followed by chromatography as described in Example 5(v) gave the title compound, m.p. 257° C. (decomp). Found: C,55.00; H,6.70; N,19.55. C16H23N5O2S requires: C,54.99; H,6.63; N,20.04%.

Sources & evidence

ORD record
ord-e02700399cf74164ac8b15aaac89869b
Source dataset
uspto-grants-1988_11
Patent number
US04788196

Reaction notes

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