HCID 70541896, compound → HCID 20522818, compound

HRID 223241Notes

Reaction equation

HRID 223241 reaction equation
[O:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH:2]1[C:7]([O:10][CH2:11][CH2:12]Cl)(O)C>O>[CH:2]1([CH2:7][O:10][CH2:11][CH2:12][O:1][CH2:2][CH2:7][OH:10])[C:3]2[C:4](=[CH:3][CH:4]=[CH:5][CH:6]=2)[CH2:5][CH2:6][O:1]1

Participants

3

Reactant 1

HCID 70541896HCID 70541896, compound

Product 1

HCID 20522818HCID 20522818, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Furthermore, various 1-hydroxymethylisochromans can be first treated with tetrahydropyranyl chloroethoxyethanol and then with acid and water to yield the corresponding 2-[2-((isochroman-1-yl)methoxy)ethoxy]ethanol.

Sources & evidence

ORD record
ord-d2d78ce44bd341a9b07aeca9d2ec253e
Source dataset
uspto-grants-1982_10
Patent number
US04352805

Reaction notes

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