7beta-Amino-3(3-oxobutyryloxymethyl)-3-cephem-4-carboxylic acid → HCID 178468093, compound

HRID 2232416Notes

Reaction equation

HRID 2232416 reaction equation
[NH2:1][C:2]1[S:3][CH:4]=[C:5](/[C:7](=[N:11]/[O:12][CH:13]([CH3:15])[CH3:14])/[C:8]([OH:10])=O)[N:6]=1.[NH2:16][C@@H:17]1[C:35](=[O:36])[N:19]2[C:20]([C:32]([OH:34])=[O:33])=[C:21]([CH2:24][O:25][C:26](=[O:31])[CH2:27][C:28](=[O:30])[CH3:29])[CH2:22][S:23][C@H:18]12>>[NH2:1][C:2]1[S:3][CH:4]=[C:5](/[C:7](=[N:11]/[O:12][CH:13]([CH3:15])[CH3:14])/[C:8]([NH:16][C@@H:17]2[C:35](=[O:36])[N:19]3[C:20]([C:32]([OH:34])=[O:33])=[C:21]([CH2:24][O:25][C:26](=[O:31])[CH2:27][C:28](=[O:30])[CH3:29])[CH2:22][S:23][C@H:18]23)=[O:10])[N:6]=1

Participants

3

Reactant 2

HCID 117819897beta-Amino-3(3-oxobutyryloxymethyl)-3-cephem-4-carboxylic acidHCID 12766129HCID 12766129, compound

Product 1

HCID 178468093HCID 178468093, compound

Procedure

Starting from 2-(2-aminothiazol-4-yl)-2(Z)-isopropoxyiminoacetic acid and 7β-amino-3-(3-oxobutyryloxymethyl)-3-cephem-4-carboxylic acid, the titled compound is obtained by the procedure of Reference Example 3.

Sources & evidence

ORD record
ord-ae52ee2a1f894254a9626be92f23b3db
Source dataset
uspto-grants-1988_11
Patent number
US04788185

Reaction notes

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