HCID 15144281, compound → HCID 13604642, compound
Reaction equation
[NH2:1][C:2]1[S:3][CH:4]=[C:5](/[C:7](=[N:15]/[OH:16])/[C:8]([O:10][CH2:11][CH2:12][S:13][CH3:14])=[O:9])[N:6]=1.Br[CH:18]([CH2:26][CH2:27][CH3:28])[C:19]([O:21][C:22]([CH3:25])([CH3:24])[CH3:23])=[O:20]>>[NH2:1][C:2]1[S:3][CH:4]=[C:5](/[C:7](=[N:15]/[O:16][CH:18]([C:19]([O:21][C:22]([CH3:23])([CH3:25])[CH3:24])=[O:20])[CH2:26][CH2:27][CH3:28])/[C:8]([O:10][CH2:11][CH2:12][S:13][CH3:14])=[O:9])[N:6]=1Participants
3
Procedure
Starting from 2-methylthioethyl 2-(2-aminothiazol-4-yl)-2(Z)-hydroxyiminoacetate and tert-butyl 2-bromovalerate, the above-identified compound is obtained by the procedure of Reference Example 16.
Workup
- customthe above-identified compound is obtained by the procedure of Reference Example 16
Sources & evidence
- ORD record
- ord-7b9d69f9b1434defb09d0023457fb517
- Source dataset
- uspto-grants-1988_11
- Patent number
- US04788185
Reaction notes
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