N-bromobutanimide → HCID 13604643, compound

HRID 2232426Notes

Reaction equation

HRID 2232426 reaction equation
[NH2:1][C:2]1[S:3][CH:4]=[C:5](/[C:7](=[N:11]/[O:12][CH2:13][C:14]([O:16][C:17]([CH3:20])([CH3:19])[CH3:18])=[O:15])/[C:8]([OH:10])=[O:9])[N:6]=1.[Br:21]N1C(=O)CCC1=O>CO>[NH2:1][C:2]1[S:3][C:4]([Br:21])=[C:5](/[C:7](=[N:11]/[O:12][CH2:13][C:14]([O:16][C:17]([CH3:20])([CH3:19])[CH3:18])=[O:15])/[C:8]([OH:10])=[O:9])[N:6]=1

Participants

4

Reactant 2

HCID 67184N-bromobutanimideHCID 10870340HCID 10870340, compound

Product 1

HCID 13604643HCID 13604643, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Conditions

Temperature
60 °C

Procedure

A mixture of 12 g of 2-(2-aminothiazol-4-yl)-2(Z)-(tert-butoxycarbonylmethoxyimino)acetic acid and 9.54 g of N-bromosuccinimide in 100 ml of methanol is stirred at 60° C. for 2 hours.

Sources & evidence

ORD record
ord-fdeca7dd34c24fab849a4f975300fbc0
Source dataset
uspto-grants-1988_11
Patent number
US04788185

Reaction notes

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