2-(Trifluoromethyl)benzoyl chloride → HCID 21283813, compound

HRID 2232445Notes

Reaction equation

HRID 2232445 reaction equation
[Cl:1][C:2]1[CH:12]=[CH:11][C:10]([Cl:13])=[CH:9][C:3]=1[C:4](=[NH:8])[O:5][CH2:6][CH3:7].[F:14][C:15]([F:26])([F:25])[C:16]1[CH:24]=[CH:23][CH:22]=[CH:21][C:17]=1[C:18](Cl)=[O:19]>>[F:14][C:15]([F:25])([F:26])[C:16]1[CH:24]=[CH:23][CH:22]=[CH:21][C:17]=1[C:18]([N:8]=[C:4]([O:5][CH2:6][CH3:7])[C:3]1[CH:9]=[C:10]([Cl:13])[CH:11]=[CH:12][C:2]=1[Cl:1])=[O:19]

Participants

3

Reactant 2

HCID 675612-(Trifluoromethyl)benzoyl chlorideHCID 21283806HCID 21283806, compound

Product 1

HCID 21283813HCID 21283813, compound

Procedure

starting from ethyl 2,5-dichlorobenzimidate and o-trifluoromethyl-benzoyl chloride there is obtained ethyl N-(o-trifluoromethyl-benzoyl)-2,5-dichlorobenzimidate and therefrom with methylhydrazine there is obtained 3-(2,5-dichlorophenyl)-1-methyl-5-(o-trifluoromethyl-phenyl)-1H-1,2,4-triazole, m.p. 60°-63° C.;

Sources & evidence

ORD record
ord-3a3405d5cdf240df962b81bb719cea1d
Source dataset
uspto-grants-1988_11
Patent number
US04788210

Reaction notes

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