2-(Trifluoromethyl)benzoyl chloride → HCID 21283758, compound

HRID 2232446Notes

Reaction equation

HRID 2232446 reaction equation
[Cl:1][C:2]1[CH:12]=[CH:11][CH:10]=[C:9]([F:13])[C:3]=1[C:4](=[NH:8])[O:5][CH2:6][CH3:7].[F:14][C:15]([F:26])([F:25])[C:16]1[CH:24]=[CH:23][CH:22]=[CH:21][C:17]=1[C:18](Cl)=[O:19]>>[F:14][C:15]([F:25])([F:26])[C:16]1[CH:24]=[CH:23][CH:22]=[CH:21][C:17]=1[C:18]([N:8]=[C:4]([O:5][CH2:6][CH3:7])[C:3]1[C:9]([F:13])=[CH:10][CH:11]=[CH:12][C:2]=1[Cl:1])=[O:19]

Participants

3

Reactant 2

HCID 675612-(Trifluoromethyl)benzoyl chlorideHCID 18347929Ethyl 2-chloro-6-fluorobenzimidate

Product 1

HCID 21283758HCID 21283758, compound

Procedure

starting from ethyl 2-chloro-6-fluorobenzimidate and o-trifluoromethyl-benzoyl chloride there is obtained ethyl N-(o-trifluoromethyl-benzoyl)-2-chloro-6-fluorobenzimidate and therefrom with methylhydrazine there is obtained 3-(2-chloro-6-fluorophenyl)-1-methyl-5-(o-trifluoromethyl-phenyl)-1H-1,2,4-triazole, m.p. 80°-84° C.;

Sources & evidence

ORD record
ord-b8bfd1440ca146f691ccb2c85fb0c3ad
Source dataset
uspto-grants-1988_11
Patent number
US04788210

Reaction notes

Loading…