2-(Trifluoromethyl)benzoyl chloride → HCID 21283760, compound

HRID 2232448Notes

Reaction equation

HRID 2232448 reaction equation
[Cl:1][C:2]1[CH:12]=[C:11]([F:13])[CH:10]=[CH:9][C:3]=1[C:4](=[NH:8])[O:5][CH2:6][CH3:7].[F:14][C:15]([F:26])([F:25])[C:16]1[CH:24]=[CH:23][CH:22]=[CH:21][C:17]=1[C:18](Cl)=[O:19]>>[F:14][C:15]([F:25])([F:26])[C:16]1[CH:24]=[CH:23][CH:22]=[CH:21][C:17]=1[C:18]([N:8]=[C:4]([O:5][CH2:6][CH3:7])[C:3]1[CH:9]=[CH:10][C:11]([F:13])=[CH:12][C:2]=1[Cl:1])=[O:19]

Participants

3

Reactant 2

HCID 675612-(Trifluoromethyl)benzoyl chlorideHCID 21283740HCID 21283740, compound

Product 1

HCID 21283760HCID 21283760, compound

Procedure

starting from ethyl 2-chloro-4-fluorobenzimidate and o-trifluoromethyl-benzoyl chloride there is obtained ethyl N-(o-trifluoromethyl-benzoyl)-2-chloro-4-fluorobenzimidate and therefrom with methylhydrazine there is obtained 3-(2-chloro-4-fluorophenyl)-1-methyl-5-(o-trifluoromethyl-phenyl)-1H-1,2,4-triazole, m.p. 67°-69° C.;

Sources & evidence

ORD record
ord-6fc6ed0b5c0c4421bd6e0b5c0386e724
Source dataset
uspto-grants-1988_11
Patent number
US04788210

Reaction notes

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