2-(Trifluoromethyl)benzoyl chloride → HCID 21283749, compound

HRID 2232450Notes

Reaction equation

HRID 2232450 reaction equation
[Cl:1][C:2]1[C:3]([F:13])=[C:4]([CH:10]=[CH:11][CH:12]=1)[C:5](=[NH:9])[O:6][CH2:7][CH3:8].[F:14][C:15]([F:26])([F:25])[C:16]1[CH:24]=[CH:23][CH:22]=[CH:21][C:17]=1[C:18](Cl)=[O:19]>>[F:14][C:15]([F:25])([F:26])[C:16]1[CH:24]=[CH:23][CH:22]=[CH:21][C:17]=1[C:18]([N:9]=[C:5]([O:6][CH2:7][CH3:8])[C:4]1[CH:10]=[CH:11][CH:12]=[C:2]([Cl:1])[C:3]=1[F:13])=[O:19]

Participants

3

Reactant 2

HCID 675612-(Trifluoromethyl)benzoyl chlorideHCID 21283785HCID 21283785, compound

Product 1

HCID 21283749HCID 21283749, compound

Procedure

starting from ethyl 3-chloro-2-fluorobenzimidate and o-trifluoromethyl-benzoyl chloride there is obtained ethyl N-(o-trifluoromethyl-benzoyl)-2-fluoro-3-chlorobenzimidate and therefrom with methylhydrazine there is obtained 3-(3-chloro-2-fluorophenyl)-1-methyl-5-(o-trifluoromethyl-phenyl)-1H-1,2,4-triazole, m.p. 137°-140° C.;

Sources & evidence

ORD record
ord-34aecfe84ef0405c864525ffcc7e8033
Source dataset
uspto-grants-1988_11
Patent number
US04788210

Reaction notes

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