2-(Trifluoromethyl)benzoyl chloride → HCID 21283732, compound

HRID 2232453Notes

Reaction equation

HRID 2232453 reaction equation
[C:1]([C:3]1[CH:13]=[CH:12][CH:11]=[CH:10][C:4]=1[C:5](=[NH:9])[O:6][CH2:7][CH3:8])#[N:2].[F:14][C:15]([F:26])([F:25])[C:16]1[CH:24]=[CH:23][CH:22]=[CH:21][C:17]=1[C:18](Cl)=[O:19]>>[F:14][C:15]([F:25])([F:26])[C:16]1[CH:24]=[CH:23][CH:22]=[CH:21][C:17]=1[C:18]([N:9]=[C:5]([O:6][CH2:7][CH3:8])[C:4]1[CH:10]=[CH:11][CH:12]=[CH:13][C:3]=1[C:1]#[N:2])=[O:19]

Participants

3

Reactant 2

HCID 675612-(Trifluoromethyl)benzoyl chlorideHCID 11309811Ethyl 2-cyanobenzenecarboximidate

Product 1

HCID 21283732HCID 21283732, compound

Procedure

starting from ethyl o-cyanobenzimidate and o-trifluoromethyl-benzoyl chloride there is obtained ethyl N-(o-trifluoromethyl-benzoyl)-o-cyanobenzimidate and therefrom with methylhydrazine there is obtained 3-(o-cyanophenyl)-1-methyl-5-(o-trifluoromethyl-phenyl)-1H-1,2,4-triazole, m.p. 96.5°-99° C.

Sources & evidence

ORD record
ord-d7b93331b52c4650954fb321311c124a
Source dataset
uspto-grants-1988_11
Patent number
US04788210

Reaction notes

Loading…