HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-phenyl-1-isoquinolinepropanoate → HCID 13769158, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-phenyl-1-isoquinolinepropanoate | HCID 13769243 | — |
| Solvent | Diethylamine | HCID 8021 | — |
| Product | HCID 13769158 | HCID 13769158 | 42.2% |
Reaction Steps
The procedure is as in Example 1, starting with ethyl 3-phenyl-1-isoquinolinepropionate (6.1 g) and diethylamine (30 cc). The crude product is purified by means of 4 successive chromatographic separations on silica gel, using a cyclohexane/ethyl acetate (7:3 by volume) mixture as eluant. N,N-Diethyl-3-phenyl-1-isoquinolinepropanamide (1.4 g), m.p. 58° C., is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04788199 |
| Source dataset | uspto-grants-1988_11 |
| ORD ID | ord-cb1ca8cb8af0453a95e0a4fcbd5a91f7 |
| Source note | uspto-grants-1988_11 |