HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethylamine → HCID 13769166, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethylamine | HCID 8021 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | HCID 21283570 | HCID 21283570 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 13769166 | HCID 13769166 | — |
Reaction Steps
The procedure is as in Example 7, starting with 2-(2-pyridyl)-4-quinazolinepropanoic acid (1.34 g), carbonyldiimidazole (0.93 g) and diethylamine (1 cc) in dimethylformamide (25 cc). After chromatography on silica gel with a chloroform/methanol (95:5 by volume) mixture as eluant, and crystallization in ethyl acetate, N,N-diethyl-2-(2-pyridyl)-4-quinazolinepropanamide (0.58 g), m.p. 130° C. is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04788199 |
| Source dataset | uspto-grants-1988_11 |
| ORD ID | ord-b676a0e08c194600b6b406d716859c94 |
| Source note | uspto-grants-1988_11 |