HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 13769199, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | Chloro-N,N-diethylacetamide | HCID 16844 | — |
| Reactant | HCID 178517442 | HCID 178517442 | — |
| Solvent | Methyl Ethyl Ketone | HCID 6569 | — |
| Product | HCID 13769199 | HCID 13769199 | 6.5% |
Reaction Steps
The procedure is as in Example 47, starting with 3-phenyl-1-isoquinolinol (5.1 g), N,N-diethylchloroacetamide (3.8 g), sodium carbonate (4.8 g) and cuprous iodide (1.15 g) in 2-butanone (100 cc). After 2 chromatographic separations on silica gel with chloroform as eluant and crystallization of the product in petroleum ether, N,N-diethyl-(3-phenyl-1-isoquinolyl)oxyacetamide (0.5 g), m.p. 102° C., is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04788199 |
| Source dataset | uspto-grants-1988_11 |
| ORD ID | ord-7b6eb0838d3549d98ebadc0d7ee3dbfb |
| Source note | uspto-grants-1988_11 |