HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethylamine → HCID 13769161, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethylamine | HCID 8021 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | HCID 9811219 | HCID 9811219 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 13769161 | HCID 13769161 | — |
Reaction Steps
The procedure is as in Example 85, starting with laevorotatory α-methyl-2-phenyl-4-quinazolinepropanoic acid (2 g) in tetrahydrofuran (20 cc), carbonyldiimidazole (1.65 g) and diethylamine (1.05 cc). After two recrystallizations in isopropyl ether, dextrorotatory N,N-diethyl-α-methyl-2-phenyl-4-quinazolinepropanamide (1.3 g), m.p. 93.8° C., is isolated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04788199 |
| Source dataset | uspto-grants-1988_11 |
| ORD ID | ord-f31eecda929a43679b2d6b4750775eff |
| Source note | uspto-grants-1988_11 |