HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethylamine → HCID 9951702, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethylamine | HCID 8021 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | HCID 21283606 | HCID 21283606 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 9951702 | HCID 9951702 | — |
Reaction Steps
The procedure is as in Example 7, starting with 2-(4-nitrophenyl)-4-quinazolinepropanoic acid (1.35 g), carbonyldiimidazole (0.82 g) and diethylamine (0.9 cc) in anhydrous tetrahydrofuran (20 cc). After chromatography on silica gel with ethyl acetate as eluant, and recrystallization in ethyl acetate, N,N-diethyl-2-(4-nitrophenyl)-4-quinazolinepropanamide (0.35 g), m.p. 168° C., is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04788204 |
| Source dataset | uspto-grants-1988_11 |
| ORD ID | ord-1c9d4359446b405ca97bd9fda2674b36 |
| Source note | uspto-grants-1988_11 |