Methanol → HCID 13769188, compound

Participants

Reaction Steps

The procedure is as in Example 37, starting with 3-(4-methoxyphenyl)-1-isoquinolinol (10 g), triethylamine (16 g) and diethylcarbamoyl chloride (21.7 g) in dimethylformamide (100 cc). After chromatograpy on silica gel, initially with a cyclohexane/ethyl acette (1:1 by volume) mixture and the second time with a tolune/methanol (98:2 by volume) mixture as eluants, and crysallization in 80% strength aqueous ethanol, 3-(4-methoxypenyl)-1-isoquinolyl diethylcarbamate (0.7 g), m.p. 84° C., is obtained.

Provenance & Evidence