HuagongsheHuagongshe Chemistry Print Report · For research reference only
Santonox → 2-(5-Phenyl-1-hydroxypentyl)-2-oxiranecarboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Santonox | HCID 7308 | — |
| Reactant | m-Chloroperbenzoic acid | HCID 70297 | — |
| Reactant | beta-Hydroxy-alpha-methylenebenzeneheptanoic acid methyl ester | HCID 14348901 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | 2-(5-Phenyl-1-hydroxypentyl)-2-oxiranecarboxylic acid methyl ester | HCID 14348902 | — |
Reaction Steps
A solution of 11.2 g (45 mmol) of β-hydroxy-α-methylenebenzeneheptanoic acid methyl ester in 300 ml of 1,2-dichloroethane is treated with 200 mg of 4,4'-thiobis(6-t-butyl-m-cresol) and 24.5 g (138 mmol) of m-chloroperoxybenzoic acid. The mixture is heated to reflux under nitrogen for 26 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04788304 |
| Source dataset | uspto-grants-1988_11 |
| ORD ID | ord-2dd5530f6dde4afbad48bab534e5a5a3 |
| Source note | uspto-grants-1988_11 |