HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → 2,3-Dichloro-4,5-difluorobenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 2,3-Dichloro-4,5-difluorobenzamide | HCID 14096368 | — |
| Product | 2,3-Dichloro-4,5-difluorobenzoic acid | HCID 13938036 | — |
Reaction Steps
A mixture of 2,3-dichloro-4,5-difluorobenzamide (0.5 g) and 18N-sulfuric acid (2.5 ml) was stirred at 125° to 135° C. for 9 hours, and then poured into ice water. After standing overnight, the resulting precipitate was collected by filtration and recrystallized from hexane-benzene to give the title compound (0.3 g) as colorless prisms.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04788320 |
| Source dataset | uspto-grants-1988_11 |
| ORD ID | ord-2f8088c4d6bf41d3b97b1ca46b882c37 |
| Source note | uspto-grants-1988_11 |