Acetic Anhydride → 3-(Dimethylamino)propyl acetate

HRID 223269Notes

Reaction equation

[CH3:1][N:2]([CH3:7])[CH2:3][CH2:4][CH2:5][OH:6].[C:8](OC(=O)C)(=[O:10])[CH3:9]>>[N:2]([CH2:3][CH2:4][CH2:5][O:6][C:8]([CH3:9])=[O:10])([CH3:7])[CH3:1]

Participants

Reactant 2

HCID 7918Acetic Anhydride

HCID 766463-(Dimethylamino)-1-propanol

Product 1

HCID 5471193-(Dimethylamino)propyl acetate

Procedure

14.4 g of 3-dimethylamino-1-propanol and 14.3 g of acetic anhydride are reacted and worked up as described in Example 7. Yield: 14.9 g (73.1%) of analytically pure product (analysis by gas chromatography) with a boiling point of 53° C./12 torr.

Sources & evidence

ORD record: ord-1a582c10081246b8a760932cb9b052c0
Source dataset: uspto-grants-1982_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04352913

Reaction notes

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