HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylamine → HCID 14994109, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylamine | HCID 7912 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | 3,3'-Bis(trifluoromethyl)benzophenone | HCID 599788 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Solvent | Hexane | HCID 8058 | — |
| Solvent | N-Ethylidene-2-methylpropan-2-amine | HCID 138901 | — |
| Product | HCID 14994109 | HCID 14994109 | — |
Reaction Steps
The compound was prepared according to the procedure described in Example 84. The following reagents were used: 3,3'-bis(trifluoromethyl)benzophenone (31.8 g), diisopropylamine (32.2 mL), 1.6M n-butyl lithium in hexane (144 mL), acetaldehyde N-tert-butylimine (14.75 mL) diethyl chlorophosphonate (16.6 mL) and tetrahydrofurane (200 mL). After the usual work up, the product was purified by HPLC to give 30,8 g of 3,3-bis[3-(trifluoromethyl)phenyl]-2-propenal as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04788206 |
| Source dataset | uspto-grants-1988_11 |
| ORD ID | ord-6cd21693d95141d1b824b39801708bae |
| Source note | uspto-grants-1988_11 |