4-Nitrophenol → HCID 14347310, compound

HRID 2232765Notes

Reaction equation

HRID 2232765 reaction equation
[C:1]1([C:7]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[CH:8]/[CH:9]=[CH:10]/[C:11]([OH:13])=[O:12])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[N+:20]([C:23]1[CH:28]=[CH:27][C:26](O)=[CH:25][CH:24]=1)([O-:22])=[O:21].C1(N=C=NC2CCCCC2)CCCCC1>ClCCl>[N+:20]([C:23]1[CH:28]=[CH:27][C:26]([O:12][C:11](=[O:13])/[CH:10]=[CH:9]/[CH:8]=[C:7]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)=[CH:25][CH:24]=1)([O-:22])=[O:21]

Participants

5

Reactant 3

HCID 9804-NitrophenolHCID 10868DicyclohexylcarbodiimideHCID 14347235HCID 14347235, compound

Product 1

HCID 14347310HCID 14347310, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

As in Example 115, (E)-5,5-diphenyl-2,4-pentadienoic acid (lg) and 4-nitrophenol (0.7 g) in dichloromethane (10 mL) was treated with 1,3-dicyclohexylcarbodiimide (0.824 g). The mixture was stirred at 0°-5° C. for 10 minutes, then at room temperature for 45 minutes. After the usual work up, the ester was crystallized from 2-propanol to yield 1.1 g of (E)-5,5-diphenyl-2,4-pentadienoic acid 4-nitrophenyl ester mp 113°-115° C.

Workup

  1. waitat room temperature for 45 minutes
  2. customAfter the usual work up, the ester was crystallized from 2-propanol

Sources & evidence

ORD record
ord-cef3931f66384e9ba8d2307104e73745
Source dataset
uspto-grants-1988_11
Patent number
US04788206

Reaction notes

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