Sodium Hydroxide → HCID 14347272, compound

Participants

Reaction Steps

In the manner described in Example 99, (2E,4Z)-5-(4-methoxyphenyl)-5-phenyl-2,4-pentadienoic acid methyl ester (6.4 g) was saponified in a refluxing mixture of methanol (30 mL) and 2N NaOH (23 mL). After 2.5 hours the reaction was worked up in the usual fashion and the crude acid was crystallized from 2-propanol to yield 4.25 g of (2E,4Z)-5-(4-methoxyphenyl)-5-phenyl-2,4-pentadienoic acid. A sample was recrystallized from 2-propanol to give the analytical specimen, mp 184°-185° C.

Provenance & Evidence