Acetic acid, 2-(triphenylphosphoranylidene)-, methyl ester → HCID 86742579, compound

Participants

Reaction Steps

As described in Example 99, (E)-3-(4-methoxyphenyl)-2-heptenal (10 g) was treated with (carbomethoxymethylene)triphenylphosphorane (17 g) in carbon tetrachloride (70 mL) and dichloromethane (15 mL) for 4 days at room temperature. The ester was isolated in the normal way and purified by HPLC (ether-hexane; 1:9) to furnish 8 g of (E,E)15-(4-methoxyphenyl)-2,4-nonadienoic acid methyl ester, as an oil.

Provenance & Evidence