Sodium Hydroxide → HCID 14347302, compound

Participants

Reaction Steps

As described in Example 99, (E,E)-5-(3-methoxyphenyl)-2,4-nonadienoic acid methyl ester (6.41 g) was saponified in a refluxing mixture of methanol (30 mL) and 2N NaOH (30 mL). After 3 hours the reaction was worked up in the usual way and the crude acid was crystallized from hexane to furnish 4.86 g of (E,E)-5-(3-methoxyphenyl)-2,4-nonadienoic acid, mp 77.5°-78.5° C.

Provenance & Evidence