Sodium Hydroxide → HCID 14347294, compound

Participants

Reaction Steps

As described in Example 99, (2E,4Z)-5-(4-methoxyphenyl)-2,4-decadienoic acid methyl ester (3.6 g) was saponified in a refluxing mixture of methanol (40 mL) and 1N NaOH (40 mL). After 45 minutes the acid was isolated in the usual way and crystallized from ether-hexane to give 3.0 g of (2E,4Z)-5-(4-methoxyphenyl)-2,4-decadienoic acid, mp 86.5°-87.5° C.

Provenance & Evidence