Acetic acid, 2-(triphenylphosphoranylidene)-, methyl ester → HCID 86742584, compound

Participants

Reaction Steps

As described in Example 99, (Z)-3-(3-fluorophenyl)-2-octenal (6.2 g) was treated with (carbomethoxymethylene)triphenylphosphorane (10.5 g) in dichloromethane (50 mL) for 4 days at room temperature. The ester was isolated in the usual way and furnished 6.6 g of (2E,4Z)-5-(3-fluorophenyl)-2,4-decadienoic acid methyl ester as an oil.

Provenance & Evidence